Since 2006 in partnership with local Tanzanian organisation, Orphans and Social Development Organisation (OSDO), Youth Off The Streets Overseas Relief Fund has recognised that education is key to giving children the best possibilities in life and breaking the cycle of poverty. With Tanzania having the lowest rate of secondary school attendance in Africa (around 7%), the two organisations saw a huge need for secondary education to be accessible for all children in Tanzania. From here, the idea of building a secondary school started to become a reality. In 2007 contruction started on St James Kilolo Secondary School. St James School is located in a remote area of the Iringa region. This remote site was chosen to accommodate orphans and children from the surrounding local villages, as they previously had no access to secondary school education.
Through OSDO, Youth Off The Streets Overseas Relief Fund has also been able to support other projects in the Iringa region of Tanzania. Youth Off The Streets Overseas Relief provides assistance at St Johns Orphanage for school fees and food. As well as St Johns Orphanage, Youth Off The Streets Overseas Relief Fund has partnered with Migoli Hospital to assist with capital works. Migoli Hospital serves remote villages and in particular, provides treatment and respite for people suffering from HIV and malaria.